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Now customize the name of a clipboard to store your clips. of Surgery; 2 Historical Aspects. Peptic Ulcer Disease: Introduction Peptic ulcer disease represents a serious medical problem. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Etiology and pathophysiology of peptic ulcer. You can change your ad preferences anytime. Clipping is a handy way to collect important slides you want to go back to later. Looks like you’ve clipped this slide to already. -… Log in Upload File. 1. Epidemiology • Peptic ulcers are common and it has been estimated that up to 10% of the population has an ulcer and annual incidence of symptomatic peptic ulcer about 0.3%. Ulcer margins are regular, slightly elevated due to adjacent chronic gastritis. There are various risk factors for the development of peptic ulcer disease, but the most important ones are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs). The genetics of peptic ulcer disease. Epidemiology of peptic ulcer. Sina Hospital. Despite the popular belief that peptic ulcers are caused by spicy foods or stress, the reality is that most of the time, peptic ulcers are caused by infection with a bacterium called Helicobacter pylori or use of NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen; ulcers caused by NSAIDs are associated with increased risk of complications. Often, they can tell you the exact timeof the perforation. A peptic ulcer in the upper part of the small intestine (i.e. Treatment of peptic ulcers varies depending on the etiology and clinical presentation (see Guidelines). Chronic peptic ulcer it is caused by high chlorhydro-peptic gastric secretion, as a result of either parietal cell hyperplasia, excessive secretory response (i.e., psychological stress) or impaired inhibition of stimulatory mechanism such as gastrin release (as in chronic renal failure or hyperparathyroidism). Fig: Peptic ulcer disease Causes or Reasons for Peptic Ulcer Disease: The different causes for peptic ulcer are-Infection with Helicobacter pylori (H. Pylori), Use of painkillers called nonsteroidal anti-inflammatory drugs such as Ibuprofen, Aspirin, and Naproxen. - Microscopic anatomy. Dr. J.H. Table 2 illustrates data regarding peptic ulcer. The prevalence of peptic ulcer and gastric ulcer was 9.4% and 4.7% in Taiwan, respectively [1,2]. Barnard ; Dept. Document presentation format: On-screen Show (4:3) Company: org Other titles: Arial Wingdings Times New Roman Network 1_Network 2_Network 3_Network 4_Network 5_Network 6_Network 7_Network 8_Network 9_Network 10_Network 11_Network Peptic Ulcer Disease Definition Peptic Ulcers: Gastric & Dudodenal PUD Demographics Comparing Duodenal and Gastric Ulcers Duodenal Ulcers Gastric Ulcers … Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. Bleeding is also the major cause of mortality in patients older than 65 years [15]. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. She looked for a PCP’s advice as she had a tarry stool in the early morning which she had never experienced before. Increased gastric acid secretion. Title: Peptic Ulcer Disease 1 Peptic Ulcer Disease . The breath test is the most accurate. INTRODUCTION Peptic ulcer disease (PUD) is a common disorder that affects millions of individuals worldwide It is accounting for roughly 10% of medical costs for digestive diseases Higher prevalence in developing countries H. Pylori is sometimes associated with socioeconomic status and poor hygiene In the US Lifetime prevalence is ~10%. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. Download Peptic Ulcer Disease PowerPoint templates (ppt) and Google Slides themes to create awesome presentations. If you continue browsing the site, you agree to the use of cookies on this website. Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. Peptic Ulcer. Dordrecht, Kluwer Academic Publishers, 1991, pp 273–282. Location and symptoms. Duodenal ulcer formation is related to hypersecretion of acid, possibly caused by overactive vagal stimulation. At least one person in every ten is likely to have a Peptic Ulcer at one time or another. PEPTIC ULCER DISEASE (Acid – pepsin ulcer disease) G JUMBI SURGICAL ANATOMY • ANATOMY (Stomach and duodenum) -gross anatomy. Location and symptoms. Gastric ulcer: It occurs in stomach particularly in lower half portion. out of 18. Peptic ulcer are among the most common known to man. Causes. Peptic ulcer disease (PUD) is one of the commonest diseases seen throughout the world. Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). Eleven questions were scored on a linear scale and a symptom score was calculated. Laboratory tests for H. pylori. Ulcers are deep lesions penetrating through the entire thickness of the gastrointestinal tract mucosa and muscularis mucosa. Document presentation format: On-screen Show (4:3) Company: org Other titles: Arial Wingdings Times New Roman Network 1_Network 2_Network 3_Network 4_Network 5_Network 6_Network 7_Network 8_Network 9_Network 10_Network 11_Network Peptic Ulcer Disease Definition Peptic Ulcers: Gastric & Dudodenal PUD Demographics Comparing Duodenal and Gastric Ulcers Duodenal Ulcers Gastric Ulcers … Epidemiology. A peptic ulcer in a child looks the same as it does in an adult, and many of the aetiologies of peptic ulcer disease in children are similar to those in adults. -… Log in Upload File. Ulcer :- An Ulcer is a discontinuity or break in a bodily membrane, or breach in the epithelium . 2009 Jan;33(1):80-5. doi: 10.1007/s00268-008-9796-1. Peptic ulcer. It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. AIMST University, Malaysia. 2. Read Irritable Bowel Syndrome: Psychosocial Assessment and Treatment | eBook... No public clipboards found for this slide. In chronic condition depth can go to the submucosal layer and sometimes perforate the serosa. peptic ulcer disease.PPT 1. Peptic ulcers: All four agents are equally effective in promoting healing of duodenal and gastric ulcers. Perforated peptic ulcer: clinical presentation, surgical outcomes, and the accuracy of the Boey scoring system in predicting postoperative morbidity and mortality World J Surg. • Duodenal ulcers are four times as common as gastric ulcers and occur mainly in the duodenal cap. Gastroenterologist and hepatologist. An unstable patient with upper gastrointestinal ( GI ) hemorrhage from 327,000 deaths in 2013 from..., produced by acid-pepsin aggression gastric vs. duodenal ulcers known to man diagnostic and therapeutic challenges 2013 down from deaths... 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